This shrine celebrates Persephone's descent to and return from the UnderWorld -- a metaphor for what it feels like to undergo treatment for breast cancer, and then to return to the everyday world.
The left inside panel shows the (frightening) descent. The right inside panel shows what happens to us in the UnderWorld: the crude, primitive, forgotten/hidden parts of ourselves are recovered, refined, and reformed into something we can bring back and use to make our lives more authentic. As the cave-like "womb" on the top suggests, in the darkest parts of ourselves, there are jewels waiting to be discovered.
On the back, the skeletal bones of death stand beside the fruits of life. Without the death of the old there can be no new growth. To live authentic lives, we need both.